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TDM, Toxicology, Vitamins, and Tumor Markers

ACTHoo

Lung Cancer

CA 15-3

breast

CA 125

ovaries, endometrial

Calcitonin

medullary thyroid cancer (MTC)

ALP(B)

liver, bone

hCG

Ovarian, trophoblestic, testicular; tests B-subunit

PSA

dSA w/ DRE

CEA

colorectal; lungs, breast, gastrointestinal

LD (Lady Daisy always NAGN)

Non-hodgkins lymphoma, Acute Leukemia, Germ cell testicular cancer, neuroblastoma

IMMunogloBulins

Multiple Myeloma, Bence jones; electrophoresis testing, g-globulin region

AFP

1 ng/L; Protein - hepatocellular carcinoma; Feto - Germ Cell Testicular cancer

antiELEPTIC

phenny takes acid for seizures

Antibiotic

HM1 Barnes is sick and drives a mean van

Antineoplastics

Cancer patients take meth

CARDIOactive

A queen of hearts proclaims dis and dig

PSYCHOactive

Crazy people drive lithium tricycles

Bronchodilators

Theo the baby takes caffeine for breathing

Vitamin A RDAs

M- 900; F- 700

Vitamin D RDAs

M&F: 15

Vitamin E RDAs

M&F: 15

Vitamin K RDAs

M: 120; F: 90

Vitamin B1 RDAs

M: 1.2; F: 1.1

Vitamin B2 RDAs

M: 1.3; F: 1.1

Vitamin B3 RDAs

M: 16; F: 14

Vitamin B6 RDAs

M&F: 1.3

Vitamin B9 RDAs

M&F: 400

Vitamin B12 RDAs

M&F: 2.4

B1, 2. 3. 6. 9. & 12 names

The routinly napping privates fail chemistry

Chromium Trace Elements

M: 35; F: 25

Copper Trace Elements

M&F: 900

Manganese Trace Elements

M: 2.3; F: 1.8

Molybdenum Trace Elements

M&F: 45

Selenium Trace Elements

M&F: 55

Zinc Trace Elements

M: 11; F: 8

Fat-soluble vitamins

Vit A, D, E, and K

Water-soluble vitamins (I pee BCause of water)

B Vitamins and Vitamin C

______________________ are all trace elements (come see the corny zebras)

Copper, Selenium, Zinc, and Chromium

Vitamin A

Vision: Skin and Eye degeneration; HPLC

Vitamin D

Bone structure; Rickets and Osteomalacia; HPLC

Vitamin E

Protects membranes; Hemolytic Anemia; HPLC

Vitamin K

"Koagulation"; Hemorrhagic disease and longer PT; PT and APTT

Vitamin B1

metabolism coenzyme; B(1)riB(1)ri

Vitamin B2

FMN and FAD component; General Metabolic defect

Vitamin B3

NAD and NADP component; Pellagra

Vitamin B6

metabolism coenzyme; General Metabolic Defect

Vitamin B9

Carrier of one-carbon groups; Megaloblastic anemia; Competitive Binding Protein

Vitamin B12

Complexes with intrinsic factor to pass through mucosa; Megaloblastic Anemia, Pernicious Anemia; Competitive Binding Protein

Vitamin C

Bone synthesis, reducing agent; Scurvy

Ethanol

Impairs; drinking alcohol

Methanol

homemade alcohols

Isopropanol

rubbing alcohol

Ethylene Glycol

hydraulic fluid and antifreeze

cyanide

component of some insecticides and rodenticides; ISE

Salicylates (Aspirin)

Sally hyperventilates before her Trinder date with Al Kalosis

Acetaminophen

severe hepatotoxicity; HPLC

__________ is the most common reference method for analyte confirmation

GC-MS

Benzodiazepines are ________________________________

Zolpidem, Eszopiclone, Diazapam, Clonazepam, Alprazolam

Cocaine is an ________________

Alkaloid salt

Opiates are natural drugs such as ___________________________-

Opium, morphine, Codeine

Opiods are unnatural drugs such as _____________________________

Heroin, hydromorphone, Oxycodone

LSD is found in ___________ (rye infecting fungus)

ergot

Phencyclidine has ___________________________ properties

stimulant, depressant, anesthetic, and hallucinogenic

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