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Skeletal system part 1

What are the different types of tissue that bones are made up out of?

Bone
Cartilage

Nervous tissue

Dense connective tissue proper

Muscle

Epithelial

What are the three types of cartilage in the skeleton

Hyaline
elastic

fibrocartilage

Hyaline characteristics and locations

most abundant and provides support with flexibilty and resistance
LOCATIONS: articular, costal, respiratory, nasal

elastic cartilage characteristics and location

more elastic fiber, is able to handle repeated bending
LOCATIONS: external ear and epiglottis

Fibrocartilage characteristics and locations

great tensile strength and restsits tension (being pulled apart)
LOCATIONS: menisci of knee

intervertebral dics

Functions of bone

support
protect

anchor

mineral/growth factor storage

blood cell formation

TG(fat) storage

Hormone production

Compact VS Spongy bone

COMPACT: dense outer layer and appears smooth and solid
SPONGY: internal layer that consits of marrow. honey comb structure

Red VS Yellow marrow

RED: blood cell production and located in medullary cavities of long and flat bones
YELLOW: fat storage and can turn back into red in adults in severe anemia

MICROSCOPIC ANATOMY OF COMPACT BONE: Osteon (haversian system)

Structural unit of compact bone
group of rings/full system

paralell to axis of bone

Types of Lamellae

1) complete: covers single osteon
2) interstitial: grouped, spaces between osteon

3) circumferential: travels circumference of the bone

Haversian (central) canal

core of each osteon that containss nerves/blood vessels
travels longitudal axis of the bone

Volkmans (perforating) canals

connects harversian canals to outer vessels
travels towards the cent of the bone

Canaliculi

canals connecting adjacent lamellae in an osteon

Bone growth: Bone cells

Osteogenic cell: primordial bone cell that grows into different types, miotically active
Osteoblast: builds more bone, matrix-synthesizing cell

Osteocyte: measures how much bone is needed, monitors and maintains mineralized bone matrix

Osteoclast: gets rid of bone, reabsorbs minerals and uses them elsewhere

Two methods of ossification

Endochondrial: Bone replaces hyaline cartilage
Intramembranous: bone develops from fibrous membrane, clavicles, bone of skull

Steps for endochondrial ossification

1) bone collar forms around the diaphysis of the hyaline cartilage model
2) Cartilage in the center of diaphysis calcifies and then develops cavities

3) The periosteal bud invades the internal cavities and spongy bone forms

4) diaphysis elongates and medullary cavity forms , secondary ossification appearls in the epiphyses

5) epipyses ossify, hylaine cartilage only appearns in epiphyseal plates and articular cartilage

Bone remodelling

spongy: replaced every 3-4 years
compact: replaced every 10 years

Two sites of control

Hormonal: stimulates bone creation
Mechanical stress: Specific to certain bone or region that makes it stronger when put under a lot of stress

Fractures

Position
completeness of break

Skin penetration

Fractures: position of bone

Non-displaced: bone ends retain normal position
Displaced: bone ends are out of alignment

Fractures: completeness of bone

Complete: bone is broken through
Incomplete: bone broken only part way through

Fractures: Skin penetration

Simple (closed): bone does not penetrate skin
Compound (open): bone penetrates skin

Type of fracture: communited

bone fragments into thrhee or more pieces, common in aged who's bones are brittle

Type of fracture: compression

bone is crushed, common in porous bones, subject to extreme trauma

Type of fracture: spiral

common sports fracture, excessive twisting forces

Type of fracture: Epiphyseal

separates from diaphysis along epiphyseal plate, when cartilage cells are dying and calcification is occuring

Type of Fracture: depressed

typical skull fracture, broken bone portion is pressed inward

Type of Fracture: Greenstick

bone breaks incompletely, only one side of the shaft breaks and the other bends

Fracture repair

external reduction: Physician manually coaxes bone ends back into position
Internal Reduction: bone ends are secured surgically with pins or wires

Fracture Healing

1) hematoma forms
2) fibrocartilangous callus forms

3) bony callus forms

4) bone remodelling occurs

Bone disorders: osteomalacia

soft/weak bones due to poor mineralization
diet related or dietary digestive disorder

Bone disorder: Rickets

analogous disease in children
due to malnourishment the cartilage do not become bone fast enough and the become too long and excessively weak

epiphyseal plate cannot calcify

calcium and Vitamin D defficient

Bone disorder: osteoporosis

common in older adults after menopause
when bone resorption is greater than bone building

Treatment: calcium, vitamine D and hormone replacement therapy

Prevention: adequate nutrition, load-bearing exercise

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