Pathology unit 1
What is pathogenesis
The cause of a disease
What is a prognosis
The outcome or lifespan of a disease
What does hematoxylin stain?
Stains the nucleus purple, nucleic acids
What does Eosin stain ?
Stains the proteins purple
What would you can a cell in the G0 stage?
It is terminally differentiated and permanetly in G0, Senescent
What is a growth factor?
Made by WBCs and are the proteins surrounding stem cells which promotes differentiation
Where are somescenescent cells located?
In the heart and brain
What takes place during Immunoperoxidase staining ?
Stain contains antibodies against specific proteins, antibodies tagged with enzye result in color change
What is a characteristic of columnar epithelium ?
Protection against chemical injury, absorbic, mucus
What is a characteristic of squamous epithelium ?
Protection against mechanical and thermal injury
What is epithelium ?
The Layer of cells that line internl cavities and external body
Where is epithelium commonly located?
GI tract, skin, respiratory system, urinary system
What is a common feautre of pseudostratified epithelium?
Cillia and used to clear debris
Epithelium in stomach ?
Simple columnar
Epithelium in esophagous ?
Stratified squamous
Where would you find cuboidal epithelium ?
In the kidneys, urinary system
Define Metaplasia
The process where epithelium changes from one type to the another
What happens during Metaplasia ?
Due to excessive damage to the tissue, the stem cells will differentiate into a more resilient tissue. When prompted by surrounding growth factors
What are the functions of fibroblast?
Cell that makes components of the protein scafolding, healing response
What is the function of adipocytes?
contain triglycerides,(fat cells)
What is ground substance and what is its function ?
The gell like material between cells and fibers that is made of carbohydrates. Source of nutrients and energy