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Evolution test 1

Why Evolution is Important (3 points)

1. Diversity of life
2. Artificial selection

3. Response to ongoing environmental change

Explain artificial selection and what the selection pressure is

It's when humans choose desirable traits in organisms to reproduce over generations (driving their evolution)

humans are the selection pressure

Macro-evolutionary changes

Larger scale, long term changes that result in new species (ex. transition from water to land)

Microevolution with an example

Change in allele frequencies from one generation to the next

ex. evolution in response to climate change (brown owls becoming more common compared to gray ones due to less snow)

Genetic variation

Members of populations vary in traits they display

Genetic inheritence

Offspring tend to resemble parents

Differential reproductive success

traits that some biological lifeforms possess that differ and alter their likelihood of survival

Result of variation, inheritance, and differential reproductive success

Evolution by natural selection

Mutations

Primary source of genetic variation, each individual has ~60-180 mutations per diploid genome

What kinds of cells are heritable

Germ-line cells ARE heritable

Somatic cells AREN'T heritable

Synonymous mutation

Doesn't alter amino acid (silent)

Nonsynonymous mutation

Leads to a different encoded amino acid (can be beneficial)

Nonsense mutation

Creates new stop codon (deleterious)

Insertion mutation

Adds nucleotides to a sequence

Deletion mutation

Removes nucleotides from a sequence

In-frame mutation

addition or removal of three nucleotides from a protein-coding sequence (doesn't disrupt reading frame)

Frameshift mutation

only one amino acid is retained, more problematic

Fitness of mutation types

Beneficial mutation = greater than 1
Neutral mutation = 1

Deleterious mutation = in between 0 and 1

Lethal mutation = 0

What are the least and most common mutations

Neutral is the most common (synonymous)

Beneficial ones are the least common

Selective agent

Imposes selection pressure

Artificial vs Natural Selection

In natural selection, nature selects the most successful traits

In artificial selection, humans select the traits

Natural selection

Individuals are selected for, populations/species don't evolve

Evolution can happen when there is:

Variation, inheritance, differential reproductive success, phenotypes

Norm of reaction curves

curve for a specific genotype, reflects different phenotypes that arise from a single genotype (depending on environmental conditions)

Phenotypic plasticity

One genotype can develop into different phenotypes depedning on the environment

Fitness

The ability of individuals to survive and reproduce in the environment in which they find themselves

Relative fitness

Fitness of phenotype / fitness of most successful phenotype

Selection coefficient

how much fitnesd reduction of less fit phenotype

ex. If fitness of a phenotype is 0.4, the selection coefficient = 1 - 0.4 = 0.6

Genetic drift

random fluctuations in allele frequencies

Where is more genetic drift prevalent

smaller populations (one allele is driven to fixation in smaller populations)

What can genetic drift lead to

allele fixation (freq = 100%)

Antagonistic Pleiotropy

Trade off between fitness in diff conditions

Adaptation

Heritable, behavioural, morphological, physiological, or genetic trait evolved through natural selection

Example of adaptation

fur coats are an adaptation to living in cold climates

Exaptation (with example)

Trait thought to have evolved to serve one function is cop-opted to serve another

ex. Dinosaurs had feathers that helped thermoregulation, birds then exapted this trait to let them fly

Hypervariable immune genes in vertebrates are an example of what

Complex adaptation

Adaptation misconceptions

1. All traits are adaptations
traits can be beneficial (adaptive), neutral, or maladaptive (bad)


2. Adaptations are perfect solutions to changes

adaptations are context dependent, and can arise from random genetic mutations


3. Adaptations will always result in higher complexity

some adaptations can evolve to increase or decrease complexity


4. Adaptation is the inevitable of evolution

there are multiple non adaptive evolutionary processes

Genetic drift

random fluctuations in the frequency of an existing gene variant in a population

Gene flow

transfer of genetic material from one population to another

can sexual selection be adaptive or maladaptive?

True

Neutral theory

Genetic drift explains the fate of genetic variation

Adaptation: evolution primarily proceeds by natural selection and selection plays a dominant role in molecular evolution

Life history strategy

schedule and manner of investment in survivorship and reproduction over an individuals lifetime

Life history trade-off

Increase in one life history trait and another one being decreased as a result

Eugenics

Beliefs and practices that aim to improve the "genetic quality" of a human population (unfounded in science)

examples of Eugenics

anti immigration sentiments, belief that one race is superior

Adaptationist thinking in different contexts

The idea of different races of humans is a product of social, economic, and political processed, not genetic/biological reality

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