DOGMA_GENE EXPRESSIONS
3 sites in initiation
A-SITE (AMINOACYL) P-SITE (PEPTIDYL) E-SITE (EXIT SITE)
site of attachment of tRNA carrying an amino acid
A SITE
site where tRNA with amino acid forms peptide bond to form an amino acid chain
P SITE
eIF that binds to the small subunit of the ribosome
1, 1A and 3
eIF that brings the initiatior methionyl tRNA to small ribosomal sub-unit in P site
2
eIF that binds to the 5' cap
4E
eIF that binds to the Poly A Tail
4G
eIF that brings the mRNA with attached 4E and 4G to the small ribosomal sub unit
4A and 4B
eIF that triggers eIF 2 from mRNA-met and signals the large ribosomal unit to complex with the small sub unit
5
an enzyme that binds to the amino acid
AMINOACYL SYNTHETASE
an enzyme that catalyzes the binding of the 2nd aminomacid to the 1st amino acod to form peptide bond
PEPTIDYL TRANSFERASE
it binds with the stop codon and signals the peptidyl transferase to transfer the amino acid chain to a molecule of water
RELEASE FACTOR