3.4
what are the mechanisms of a DNA repair
DIRECT DNA REPAIR, REMOVAL OF DAMAGED REGION, REPAIR OF DNA BREAKS
it is inhibited by prokaryotes only
DIRECT DNA REPAIR
a process where it involves reversal of damage caused by radiation
PHOTOREACTIVATION
processes under the removal of damaged region
BASE EXCISION REPAIR
NUCLEOTIDE EXCISION REPAIR
MISMATCH REPAIR
what enzyme recognizes and removes a damaged nitrogenous base
GLYCOSYLASE
explain base excision repair
GYLCOSYLASE WILL RECOGNIZE AND REMOVE A DAMAGED NITROGENOUS BASE
DNA POLYMERASE WILL ADD A NEW NITROGENOUS BASE
DNA LIGASE BINDS THE NEW BASE TOGETHER
explain nucleotide excision repair
REMOVAL OF A DAMAGED POLYNUCLEOTIDE SEGMENT FROM THE AFFECTED DNA STRAND
DNA POLYMERASE ADDS NEW NUCLEOTIDE USING THE COMPLEMENTARY SEGMENT AS THE TEMPLATE
DNA LIGASE BINDS THE ADJACENT NUCLEOTIDES TOGETHER
explain mismatch repair
PAG YUNG COMPLEMENTARY BASE PAIRS NAPALITAN NG NON COMPLEMENTARY PAIR, MAGKAKAROON NG MISMATCH
THIS MISMATCH WILL BE REPAIRED FIRST BEFORE THE CELL ENTERS DIVISION
DNA POLYMERASE WILL PROOFREAD AND DETECT THE MISMATCHED BASES, REMOVE THE WRONG, INSERT THE CORRECT
under the repair of DNA breaks, this enzyme catalyzes the production of 3'OH and 5' phosphate ends to allow both ends undergo ligation
PHOSPHATASE