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3.4

mutation due to change in one base on a DNA strand replaced by another base

POINT MUTATION

purine to purine

TRANSITION

purine to pyrimidine

TRANSVERSION

lahit magkapalit, same parin amino acid product

SILENT MUTATION

pag nagkapalitan, mag iiba na rin amino acid product

MISSENSE MUTATION

the base change can change the sequence to stop codon

NONSENSE MUTATION

mutation due to insertion or deletion of one or more bases

FRAMESHIFT MUTATION

anything that has the ability to produce a mutation

MUTAGENIC AGENTS

examples of ionizing radiation

X RAY, GAMMA RAUS AND ALPHA RAYS

this radiation breaks an electron of a neutral atom converting it to a positive ion

IONIZING RADIATION

this reaction creates a highly reactive ions that can form new bonds where wala namang required

IONIZING RADIATION

example of non ionizing radiation

ultraviolet radiation

it affects pyrimidine cytosine and thymine

NON IONIZING RADIATION

it weakens double bonds between carbons of cytosine and allows water to be added to these points, thus, preventing the cytosine to form bonds leading to strand separation

PHOTOPRODUCTS

weaken double bonds between thymine and allows another thymine to bond leads to disruption of a normal T A pairing

DIMERS

this is a mutagen where you will be exposed to radiation

PHYSICAL MUTAGENS

it breaks the amino acid of a base transforming the nucleotide into another type of nucleotide

DNA REACTIVE AGENTS

example of DNA reactive agents

DEAMINATING AGENTS

it resembles purine and pyrimidine

BASE ANALOGS

a base analog that resembles thymine

BROMOURACIL

a base analog that resembles adenine

AMINOPURINE

a chemical mutagen substances that insert into the DNA strand forming a normal strand into a longer one

INTERCALATING AGENTS

a chemical mutagen wherein propyl groups are added to the backbone of the DNA that can lead to continous breakdown and mispairing of bases

ALKYLATING AGENTS

a biological agent aka jumping genes coz they have the ability to move from one region to another of the DNA

DNA TRANSPOSONS

a biological mutagen wherein you insert the genetic material into the host DNA disrupting base sequences and genetic functions

VIRUS

a bacterial biological agent wherr it triggers the formation of reactive oxygen species

HELICOBACTER PYLORI

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