A TEST- Urinary system - Angiotensin system
What does the Angiotensin system accomplish?
allows for the kidneys to regulate blood pressure
Filtration rate
remains relatively constant
What conditions might cause the filtration rate to increase?
increase in water volume
What conditions might cause the filtration rate to decrease?
decrease in water volume/dehydration
Which main hormones affect Renal Filtration?
Aldosteronc and Antidiuretic hormones
What does the Aldosterone hormone cause?
causes adrenal glands to secrete in response to changes in blood concentration of K+ or Na+
What does Aldosterone increase?
- reabsorption of Na+ in the DCT
- increased secretion of K+
What makes and releases the Antidiuretic Hormone?
The hypothalamus makes, and the pituitary gland releases
What causes the pituitary gland to release Antidiuretic hormone?
releases in response to a decrease in water concentration blood or decease in blood volume
What does the Antidiuretic hormone cause
increase in permeability of DCT and collecting ducts to reabsorb water rapidly
Where is enzyme renin produced?
the kidney
what is the function of renin
help to convert angiotensinogen into Angiotensin 1
where is angiotensinogen produced?
the liver
In what liquid tissue is angiotensinogen converted to angiotensin 1?
Plasm
ACE
Angiotensin-Converting-Enzyme
Function of ACE?
converts angiotensin 1 into angiotensin 2
Which is the most important of the 2 sites that secrete ACE?
pulmonary epithelium
Physiological effects of angiotensin 1?
positive effects ion depression and anxiety
5 major effects of Angiotensin 2?
- increased blood pressure
- sodium and water retention
- Aldosterone release
- sympathetic nervous stimulation
- vasoconstriction
Vasoconstriction effect on blood pressure?
increases
What does angiotensin 2 cause renal tubules to retain?
NA and Cl
What does water follow?
Na and Cl
if the renal tubules cause the blood to retain more sodium what happens?
The blood volume increases as the water concentration increases in response to the increase in Na/sodium
What will an increased blood volume do to the blood pressure?
increase it
Where does Angiotensin 2 act?
acts on the glomerular arterioles
What does angiotensin cause the arterioles to do?
constrict
What will vasoconstriction of the arterioles do to the systemic blood pressure?
increase
What effect will vasoconstriction of the afferent arteriole have on glomerular perfusion (filtration rate)?
decrease it (less room so less blood goes through)
What will vasoconstriction do to blood pressure
increase it
ADH
antidiuretic hormone
ADH effect on BP
increases (narrows blood vessels, produces less urine, less blood flow)