55%
erythrocytes (RBC)
to release histamine
lymphocyte
eosinophil
hematopoiesis
hemocytoblast
1. ribosome synthesis
2. hemoglobin accumulation
3. ejection of nucleus
15 days
1. hypoxia (decreased RBC, Hb, and O2)
2. kidneys release erythropoietin
3. erythropoietin stimulates red bone marrow
4. erythropoiesis increases amount of RBC
5. ability to carry O2 rises
120 days
platelets
hemostasis
thrombopoietin
megakaryoblast, promegakaryocyte, megakaryocyte
vascular spasms, platelet plug formation, coagulation
thrombin
2 antigens on RBC and 2 antibodies in plasma
agglutinogens, agglutinins
hemolytic reaction
presence or absence of D agglutinogen (Rh+ or Rh-)
Rh-
an Rh- person gets Rh+ blood
when a subject is exposed a second time to Rh+ blood if they have Rh-
mom is Rh- and the Rh+ antibodies attack and destroy the RBC of Rh+ baby
RhoGAM
hemolytic
fever, chills, headache, flushing, anxiety
shortness of breath, bronchiospasms, anxiety
myleoma
reduced RBC production
functional
irradiation, ant-leukemic drugs, bone marrow transplants