Utilisateur
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What are the two main types of COPD?
Chronic bronchitis and emphysema
What is emphysema?
Destruction of alveolar walls with enlarged air spaces
What enzyme causes alveolar destruction in emphysema?
Elastase
What is the function of alpha-1 antitrypsin?
Inhibits elastase
Which emphysema is caused by smoking?
Centriacinar emphysema
Which emphysema is caused by alpha-1 antitrypsin deficiency?
Panacinar emphysema
What happens to DLCO in emphysema?
Decreased
What is chronic bronchitis?
Productive cough for at least 3 months in 2 consecutive years
What is Reid index?
Ratio of mucous gland thickness to bronchial wall thickness
Why does cyanosis occur in chronic bronchitis?
Due to hypoxia
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