Neuro - Olfactory System
Which of the following are olfactory bulb targets?
amygdala
entorhinal cortex
olfactory tubercle
pyriform cortex
How does odorant perception differ between mammals?
number of olfactory receptor neurons
size of olfactory epithelium
size of area devoted to olfaction
True or False: Humans can distinguish isomers based on scent
true
_____ is the loss of ability to detect one or more odors
anosmia
Which 3 cells are found in the olfactory epithelium?
basal cells
supporting cells
olfactory receptor cells
Odorants initially bind to specific _____, which are concentrated on the external surface of olfactory cilia
odorant receptor proteins
Choose the correct odorant transduction pathway
odorant binds to receptor protein, Golf activated, AC3 activated, cAMP binds to channel, Ca and Na come in, depolarization
How many functional receptor proteins do humans have?
About 1000
The timing of APs is used to code for odor discrimination. This is better known as ______
temporal coding
olfactory temporal coding
The brain distinguishes individual odors by the combination of firing responses. This is better known as ______
population coding
olfactory population coding
Olfactory receptor neurons send their axons into the _____
olfactory bulbs
olfactory bulb
Each olfactory bulb contains about 2000 ______
glomeruli
True or False: Olfactory receptor neurons expressing a particular receptor gene send their axons to the same glomeruli
true
Odorant receptors with highly homologous ______ tend to be localized in the same zone of the olfactory epithelium
amino acid sequences
Is zonal organization preserved in the olfactory bulbs? Yes or No
yes
Is zonal organization preserved in the olfactory cortex? Yes or No
no
A code in which info is conveyed by the relative positions of activated neurons is known as a _______
spatial code
______ cells regulate the activity of mitral cells
granule
True or False: Granule cells can have excititory or inhibitory effects
true
Mitral cells release _____ onto Granule cells
glutamate
Granule cells release _____ onto Mitral cells
GABA
The interaction between mitral cells and granule cells is called ________ (3 words)
dendrodendritic reciprocal synapse
True or False: The purpose of dendrodendritic reciprocal synapses is to sharpen the tuning specificity of individual mitral cells to odor molecules
true