Spindles and ripples increase during _____ of neocortical slow oscillations

upstates

Memory replay is coordinated by locking hippocampal _____ to troughs of spindles during upstate of neocortical slow oscillations

sharp wave ripples

______ accompany reactivations or replay events

sharp waves

Reticular neurons release ____, which causes inhibitory post synaptic potentials

GABA

CSF flows through Aquaporin 4 channels into _____, where it gains access to brain tissues

astrocytes

Periarterial accumulation of _______ is thought to form plaques, which disrupt CSF clearance mechanisms and can lead to neurodegenerative diseases

Beta Amyloid

Glymphatic flow is the greatest during which stage of sleep?

NREM 3

3

three

nonREM 3

True or False: Older people have reduced glymphatic flow as compared to young people because of their reduced time spent in NREM 3 sleep

true

Which of the following are associated with sleep?

increase in interstitial space

increased glymphatic flow