Neuro - Sleep 3
Spindles and ripples increase during _____ of neocortical slow oscillations
upstates
Memory replay is coordinated by locking hippocampal _____ to troughs of spindles during upstate of neocortical slow oscillations
sharp wave ripples
______ accompany reactivations or replay events
sharp waves
Reticular neurons release ____, which causes inhibitory post synaptic potentials
GABA
CSF flows through Aquaporin 4 channels into _____, where it gains access to brain tissues
astrocytes
Periarterial accumulation of _______ is thought to form plaques, which disrupt CSF clearance mechanisms and can lead to neurodegenerative diseases
Beta Amyloid
Glymphatic flow is the greatest during which stage of sleep?
NREM 3
3
three
nonREM 3
True or False: Older people have reduced glymphatic flow as compared to young people because of their reduced time spent in NREM 3 sleep
true
Which of the following are associated with sleep?
increase in interstitial space
increased glymphatic flow
When is clearance of Beta Amyloid the greatest?
sleep
When is clearance of inulin the greatest?
under anesthesia