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Neuro - Olfactory System

Which of the following are olfactory bulb targets?

amygdala

entorhinal cortex

olfactory tubercle

pyriform cortex

How does odorant perception differ between mammals?

number of olfactory receptor neurons

size of olfactory epithelium

size of area devoted to olfaction

True or False: Humans can distinguish isomers based on scent

true

_____ is the loss of ability to detect one or more odors

anosmia

Which 3 cells are found in the olfactory epithelium?

basal cells

supporting cells

olfactory receptor cells

Odorants initially bind to specific _____, which are concentrated on the external surface of olfactory cilia

odorant receptor proteins

Choose the correct odorant transduction pathway

odorant binds to receptor protein, Golf activated, AC3 activated, cAMP binds to channel, Ca and Na come in, depolarization

How many functional receptor proteins do humans have?

About 1000

The timing of APs is used to code for odor discrimination. This is better known as ______

temporal coding

olfactory temporal coding

The brain distinguishes individual odors by the combination of firing responses. This is better known as ______

population coding

olfactory population coding

Olfactory receptor neurons send their axons into the _____

olfactory bulbs

olfactory bulb

Each olfactory bulb contains about 2000 ______

glomeruli

True or False: Olfactory receptor neurons expressing a particular receptor gene send their axons to the same glomeruli

true

Odorant receptors with highly homologous ______ tend to be localized in the same zone of the olfactory epithelium

amino acid sequences

Is zonal organization preserved in the olfactory bulbs? Yes or No

yes

Is zonal organization preserved in the olfactory cortex? Yes or No

no

A code in which info is conveyed by the relative positions of activated neurons is known as a _______

spatial code

______ cells regulate the activity of mitral cells

granule

True or False: Granule cells can have excititory or inhibitory effects

true

Mitral cells release _____ onto Granule cells

glutamate

Granule cells release _____ onto Mitral cells

GABA

The interaction between mitral cells and granule cells is called ________ (3 words)

dendrodendritic reciprocal synapse

True or False: The purpose of dendrodendritic reciprocal synapses is to sharpen the tuning specificity of individual mitral cells to odor molecules

true

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